KANEKA KanCap™ L is a newly developed cellulose-based Protein L resin that exhibits an increased affinity to VL region of antibody κ light chain.
The resin was designed for capture and purification of a wide range of antibody fragment formats such as scFv, Fab and F(ab’)2.
KANEKA KanCap™ L is also an alternative tool to purify full length antibody formats containing a κ light chain which poorly binds to Protein A resins.
> High binding capacity for antibody molecules containing a κ light chain
> Wide binding range for antibody molecules containing a κ light chain
Selection of the ligand having the widest binding spectra and the highest binding affinity to Fabs was made by screening multiple Protein L mutants.
| Product Name | Format | Pack size | Catalog Number |
|---|---|---|---|
| KANEKA KanCap™ L | Prepacked column | 1 mL | KPL01-C001 |
| 5 mL | KPL01-C005 | ||
| Bulk Resin | 25 mL | KPL01-B025 |
Would you like to get a PDF version? Download the KANEKA KanCap™L product brochure.
Download the Platform process for antibody fragments using cellulose based affinity chromatography resins poster.
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